Animal Models of Ophthalmic Diseases by Chi-Chao Chan

By Chi-Chao Chan

This ebook describes experimental animal types that mimic universal human ocular illnesses: herpetic keratitis, cataract, glaucoma, age-related macular degeneration, diabetic retinopathy, uveitis, retinitis pigmentosa, Graves’ sickness, and intraocular tumors. In conjunction, those types replicate the variety and application of instruments used to review human illness. global specialist clinicians talk about every one version in response to their medical adventure and the textual content is supported by way of quite a few pictures and diagrams. In describing the main pertinent animal types of ophthalmic illnesses, this publication could be of curiosity to ophthalmologists, imaginative and prescient researchers, fellows, citizens and scientific students.

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Neuroscience 137(2):447–461. 1016/j. 084 Giblin FJ (2000) Glutathione: a vital lens antioxidant. J Ocular Pharmacol Therapeut: Assoc Ocular Pharmacol Therapeut 16(2):121–135 24 Giblin FJ, Reddy VN (1980) Pyridine nucleotides in ocular tissues as determined by the cycling assay. , Reddy VN (1995) Nuclear light scattering, disulfide formation and membrane damage in lenses of older guinea pigs treated with hyperbaric oxygen. Exp Eye Res 60(3):219–235 Giblin FJ, Leverenz VR, Padgaonkar VA, Unakar NJ, Dang L, Lin LR, Lou MF, Reddy VN, Borchman D, Dillon JP (2002) UVA light in vivo reaches the nucleus of the guinea pig lens and produces deleterious, oxidative effects.

Development 133(13):2585–2593. 02424 Gong X, Li E, Klier G, Huang Q, Wu Y, Lei H, Kumar NM, Horwitz J, Gilula NB (1997) Disruption of alpha3 connexin gene leads to proteolysis and cataractogenesis in mice. Cell 91(6):833–843 Gong X, Agopian K, Kumar NM, Gilula NB (1999) Genetic factors influence cataract formation in alpha 3 connexin knockout mice. Dev Gen 24(1/2):27–32. CO;2–7 Goodenough DA (1992) The crystalline lens. A system networked by gap junctional intercellular communication. Seminars Cell Biol 3(1):49–58 Gorin MB, Yancey SB, Cline J, Revel JP, Horwitz J (1984) The major intrinsic protein (MIP) of the bovine lens fiber membrane: characterization and structure based on cDNA cloning.

Saunders Berthoud VM, Beyer EC (2009) Oxidative stress, lens gap junctions, and cataracts. Antioxid Redox Signal 11(2):339–353. 2119 Black RL, Oglesby RB, Von Sallmann L, Bunim JJ (1960) Posterior subcapsular cataracts induced by corticosteroids in patients with rheumatoid arthritis. JAMA 174:166–171 Bloemendal H, Zweers A, Vermorken F, Dunia I, Benedetti EL (1972) The plasma membranes of eye lens 2 Animal Models of Cataracts fibres. Biochemical and structural characterization. Cell Differ 1(2):91–106 Boyle DL, Takemoto L, Brady JP, Wawrousek EF (2003) Morphological characterization of the Alpha A- and Alpha B-crystallin double knockout mouse lens.

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