By Curtis A. Williams, Merrill W. Chase
Equipment in Immunology and Immunochemistry, quantity IV: Agglutination, supplement, Neutralization, and Inhibition offers info pertinent to direct and oblique agglutination reactions. This e-book covers various subject matters, together with complement-fixation strategies, isolation of supplement elements, hemolytic intermediates, complement-related proteins, and neutralization reactions.
Organized into 3 chapters, this quantity starts with an outline of test-tube agglutinations which are most well liked for blood grouping with saline agglutinins that require various mins for agglutination. this article then describes blood workforce antibodies that agglutinate pink blood cells suspended in saline. different chapters ponder the classical pathway of supplement usage. This ebook discusses besides the complexity of occasions resulting in hemolysis of erythrocytes by way of supplement. the ultimate bankruptcy offers with the facility of antitoxin to neutralize diphtheria toxin and explains the quantitative relationships among antigen and antibody.
This e-book is a beneficial source for immunologists, scientists, and study staff.
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Extra info for Agglutination, Complement, Neutralization, and Inhibition
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Boyd, Vox Sanguinis 8, 1 (1963). K . C. Atwood and S. L . Scheinberg, / . Cell. Comp. Physiol. 52, Suppl. 1, 97 (1958). 6 DIRECT HEMAGGLUTINATION 21 erythrocyte,2^ (i) changing, by chemical alteration, the specificity of lectins (and potentially of antibodies),^^-^^ (j) testing the lattice theory of immune reactions. ,^^ chromatography and affin ity chromatography have resulted in preparations that are highly purified. Using such methods, H a m m a r s t r ö m and Kabat^^ purified and character ized the anti-A lectin from the snail Helix pomatia, and Etzler and K a b a t ' ^ purified the anti-A from Dolichos biflorus.